Examination of Y-chromosomal microdeletions and partial microdeletions in idiopathic infertility in East Hungarian patients
نویسندگان
چکیده
منابع مشابه
[Y chromosome microdeletions in male infertility].
A genetic basis of infertility may exist in many men currently classified as having idiopathic infertility. Approximately 7% of infertile men harbour submicroscopic deletions of the Y chromosome that are not detectable on routine karyotype. Two candidate gene families, namely the RNA-binding motif-containing gene family, and the deleted-in-azoospermia gene family, have been cloned by deletion m...
متن کاملPartial and complete microdeletions of Y chromosome in infertile males from South of Iran
Y chromosome microdeletions are the second genetic cause of male infertility. The incidence of Y chromosome microdeletions can vary considerably depending on several factors, including patient selection criteria, population composition, and diagnostic protocols. They are associated with spermatogenic failure and lead to azoospermia or oligozoospermia. The advance in assisted reproductive techno...
متن کاملY chromosome microdeletions frequency in idiopathic azoospermia, oligoasthenozoospermia, and oligospermia
Background Genetic factors are candidates for about 30% of male infertility with sperm production-related abnormalities. Y chromosome microdeletions are responsible for around 10% of male infertility. These microdeletions generally occur in azoospermia factor on the Yq. That is often associated with the quantitative reduction of sperm. Objective The aim of this cross-sectional study was to de...
متن کاملY chromosome microdeletions in idiopathic infertile men from West Azarbaijan.
INTRODUCTION Although assisted reproduction techniques are used extensively in Iran, screening for Y chromosome microdeletions before intracytoplasmic sperm injection is often undervalued. Our aim was to investigate Y chromosome microdeletions in men with idiopathic azoospermia or severe oligospermia. MATERIALS AND METHODS In 99 selected patients with azoospermia or severe oligospermia and el...
متن کاملHigh Prevalence of Y Chromosome Partial Microdeletions in Overweight Men
BACKGROUND Microdeletions of the Y chromosome are one of the most frequent genetic causes of spermatogenic failure in infertile men. But their role in gaining weight is unclear. The present study investigated the possible association of these partial microdeletions and obesity. METHODS In a case-control study, 180 males were selected. The prevalence of microdeletions was assessed using PCR in...
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ژورنال
عنوان ژورنال: Journal of Human Reproductive Sciences
سال: 2018
ISSN: 0974-1208
DOI: 10.4103/jhrs.jhrs_12_18